To date, continuous delivery of L-DOPA is done by Duodopa, which is invasive and inconvenient. Lasting Effect is developing a unique formulation of L-DOPA prodrug, which can be loaded into the tablet and released continuously in the oral cavity.
Cognitive malfunction: Another formulation, which is particularly suitable for the Lasting Effect’s tablet, is a combination of two clinically approved drugs, one of which is neuroprotective as well as cognitive enhancer and the other has beneficial effect in treating Parkinson’s disease, particularly alleviating involuntary movements and at the same time it also enhances and prolongs the effect of the first drug.
The tablet with this drug combination can be used for the treatment of Parkinson’s disease as well as for the treatment of dementias, such as those that occur in Parkinson’s disease, minimal cognitive impairment and Alzheimer’s disease.